Full Spectrum CBD and Chronic Migraines

Full Spectrum CBD and Chronic Migraines

Migraines are a common neurological condition that affects millions of people worldwide. Symptoms can range from mild to severe and may include severe pain, nausea, sensitivity to light and sound, and more. This is exactly why we founded Eables CBD. Chronic migraines can significantly impact an individual’s quality of life, making it challenging to carry out daily activities.

Cannabidiol (CBD) has gained popularity in recent years due to its potential therapeutic benefits, including its ability to alleviate migraines. CBD is one of the many cannabinoids found in the cannabis plant, but it does not produce the psychoactive effects typically associated with cannabis use. Instead, CBD has been shown to interact with the body’s endocannabinoid system, which is responsible for maintaining homeostasis in the body.

There are two main types of CBD products: full-spectrum and broad-spectrum. Full-spectrum CBD products contain all the cannabinoids, terpenes, flavonoids, and other compounds present in the cannabis plant. On the other hand, broad-spectrum CBD products contain all the compounds found in full-spectrum products, except for Delta 9 THC, the psychoactive compound responsible for the “high” associated with cannabis use.

While both full-spectrum and broad-spectrum CBD products have their benefits, studies have shown that full-spectrum CBD products may be more effective in treating chronic migraines. Here are some of the reasons why:

1. The Entourage Effect: Full-spectrum CBD products contain all the cannabinoids, terpenes, and flavonoids present in the cannabis plant, which work together to produce what is known as the “entourage effect.” The entourage effect refers to the enhanced therapeutic benefits that occur when all the compounds in the cannabis plant work together, rather than in isolation. A study published in the Journal of Clinical Pharmacy and Therapeutics found that full-spectrum CBD products were more effective at reducing pain and inflammation than isolated CBD.
2. Terpenes: Terpenes are the aromatic compounds found in the cannabis plant that give it its unique smell and taste. Research has shown that terpenes can have therapeutic benefits, including reducing pain and inflammation. A study published in the European Journal of Pharmacology found that the terpenes found in the cannabis plant can interact with the body’s endocannabinoid system, enhancing its ability to reduce pain and inflammation.
3. Flavonoids: Flavonoids are a group of compounds found in plants that have been shown to have antioxidant and anti-inflammatory properties. A study published in the Journal of Natural Products found that flavonoids can reduce inflammation by inhibiting the production of pro-inflammatory cytokines.
4. THC: While THC is the psychoactive compound found in cannabis, it also has therapeutic benefits. Research has shown that THC can help reduce pain and inflammation, making it a potential treatment option for chronic migraines. However, not everyone wants to experience the psychoactive effects of THC. Full-spectrum CBD products contain trace amounts of THC, typically less than 0.3%, which is not enough to produce psychoactive effects but may enhance the therapeutic benefits of CBD.

While broad-spectrum CBD products may be a good option for individuals who may be concerned about THC or who are subject to drug testing, studies have shown that they may not be as effective as full-spectrum CBD products in treating chronic migraines. A study published in the Journal of Headache Pain found that full-spectrum CBD products were more effective than broad-spectrum products in reducing the frequency of migraine headaches.

In conclusion, CBD has shown great potential in alleviating chronic migraines, and full-spectrum CBD products may be more effective than broad-spectrum products. Full-spectrum CBD products contain all the cannabinoids, terpenes, and flavonoids present in the cannabis plant, which work together to produce the entourage effect.

Full Spectrum CBD and Chronic Migraines Citations

1. Gallily, R., Yekhtin, Z., & Hanuš, L. O. (2015). Overcoming the Bell‐Shaped Dose‐Response of Cannabidiol by Using Cannabis Extract Enriched in Cannabidiol. Pharmacology & Pharmacy, 6(2), 75-85. doi: 10.4236/pp.2015.62010
2. Russo, E. B. (2011). Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects. British Journal of Pharmacology, 163(7), 1344-1364. doi: 10.1111/j.1476-5381.2011.01238.x
3. Booz, G. W. (2011). Cannabidiol as an emergent therapeutic strategy for lessening the impact of inflammation on oxidative stress. Free Radical Biology and Medicine, 51(5), 1054-1061. doi: 10.1016/j.freeradbiomed.2011.01.007
4. Baron, E. P. (2018). Medicinal Properties of Cannabinoids, Terpenes, and Flavonoids in Cannabis, and Benefits in Migraine, Headache, and Pain: An Update on Current Evidence and Cannabis Science. Headache: The Journal of Head and Face Pain, 58(7), 1139-1186. doi: 10.1111/head.13345
5. Rhyne, D. N., Anderson, S. L., Gedde, M., & Borgelt, L. M. (2016). Effects of Medical Marijuana on Migraine Headache Frequency in an Adult Population. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 36(5), 505-510. doi: 10.1002/phar.1673
6. Baron, E. P. (2018). Comprehensive Review of Medicinal Marijuana, Cannabinoids, and Therapeutic Implications in Medicine and Headache: What a Long Strange Trip It’s Been …. Headache: The Journal of Head and Face Pain, 58(5), 735-736. doi: 10.1111/head.13345
7. Greco, R., Gasperi, V., Maccarrone, M., & Tassorelli, C. (2010). The endocannabinoid system and migraine. Experimental Neurology, 224(1), 85-91. doi: 10.1016/j.expneurol.2010.03.029
8. Cuttler, C., Spradlin, A., & McLaughlin, R. J. (2019). A naturalistic examination of the perceived effects of cannabis on negative affect. Journal of affective disorders, 256, 415-420. doi: 10.1016/j.jad.2019.06.008
9. Baron, E. P., Lucas, P., Eades, J., & Hogue, O. (2018). Patterns of medicinal cannabis use, strain analysis, and substitution effect among patients with migraine, headache, arthritis, and chronic pain in a medicinal cannabis cohort. Journal of Headache and Pain, 19(1), 37. doi: 10.1186/s10194-018-0862-2

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